All of Central and Eastern Europe is currently going through a very challenging period for scientific research. The challenges for Croatia appear to be even harder, as historically less than 1 pct. of Croatian GDP is spent on Research and Development. Still, there are Croatian research programs that produce excellent results on a global scale. What are these exactly? And what are the challenges that these programs, as well as Croatia as a research nation face in the next future? Using Elsevier’s SciVal, the world’s leading platform for research intelligence and research management, we will thrive to find factual answers to these questions.